Lobulated; sheets and cords of epithelioid-polygonal cells
Abundant pale eosinophilic cytoplasm with frequent vacuolation
Round-ovoid nuclei with small nucleoli and mild pleomorphism; inconspicuous mitotic activity
Prominent myxoid stroma; necrosis
IHC: brachyury
Lobulated; sheets of epithelioid-polygonal cells
Abundant pale amphophilic cytoplasm with frequent vacuolation
Round-ovoid nuclei with small nucleoli and mild pleomorphism; inconspicuous mitotic activity
Focal myxoid stroma
IHC: S100, keratin (AE1/AE3), brachyury
Lobulated; sheets and cords of epithelioid-polygonal cells
Abundant pale eosinophilic cytoplasm with frequent vacuolation
Hyperchromatic round-ovoid nuclei with small nucleoli and mild-moderate pleomorphism; inconspicuous mitotic activity
Myxoid stroma
Lobulated; sheets and cords of epithelioid-polygonal cells
Abundant pale eosinophilic cytoplasm with frequent vacuolation
Hyperchromatic round-ovoid nuclei with small nucleoli and mild-moderate pleomorphism; inconspicuous mitotic activity
Myxoid stroma
Broad anastomosing cords of epithelioid-polygonal cells
Abundant pale eosinophilic cytoplasm with frequent vacuolation
Hyperchromatic round-ovoid nuclei with small nucleoli and mild-moderate pleomorphism; inconspicuous mitotic activity
Myxoid stroma
IHC: brachyury
Lobules and anastomosing cords of epithelioid-polygonal cells
Abundant pale eosinophilic cytoplasm with vacuolation
Hyperchromatic round-ovoid nuclei with mild-moderate pleomorphism; inconspicuous mitotic activity
Hyaline cartilage and myxoid stroma
IHC: S100, keratin (AE1/AE3)