Lobulated; spindle-stellate cells in vague fascicles and clusters
Eosinophilic cytoplasm
Monomorphic ovoid nuclei; inconspicuous mitotic activity
Collagenous-myxoid stroma with thin-walled vasculature
RNA-seq: PRRX1::NCOA1 gene fusion
Variably cellular; spindle-ovoid cells in vague fascicles
Monomorphic ovoid nuclei; inconspicuous mitotic activity
Abundant collagenous stroma; thin-walled ectatic vasculature with perivascular hyalinization
RNA-seq: PRRX1::NCOA1 gene fusion
Variably cellular; spindle-ovoid cells in vague fascicles
Monomorphic ovoid nuclei; inconspicuous mitotic activity
Abundant stroma comprised of thin collagen filaments and occasional collagen rosettes; thin-walled ectatic vasculature with perivascular hyalinization
RNA-seq: PRRX1::NCOA1 gene fusion
Variably cellular; spindle-ovoid cells in vague fascicles
Monomorphic ovoid nuclei; inconspicuous mitotic activity
Abundant stroma comprised of thin collagen filaments; thin-walled ectatic-curvilinear vasculature
RNA-seq: PRRX1::NCOA1 gene fusion
Variable cellularity; spindle-ovoid cells in vague fascicles and clusters
Eosinophilic cytoplasm
Monomorphic ovoid nuclei; inconspicuous mitotic activity
Abundant stroma comprised of thin collagen filaments; thin-walled ectatic-curvilinear vasculature
IHC: S100
RNA-seq: PRRX1::NCOA1 gene fusion
PMID: 31008539
Circumscribed; cellular; spindle-ovoid cells in vague fascicles
Eosinophilic cytoplasm
Monomorphic ovoid nuclei; inconspicuous mitotic activity
Myxoid stroma with prominent thin collagen filaments; thin-walled ectatic-curvilinear vasculature
RNA-seq: PRRX1::NCOA1 gene fusion
PMID: 31008539