Hypocellular fascicles of spindle cells with admixed adipocytes
Spindle cells have eosinophilic cytoplasm; nuclei are ovoid with mild-moderate atypia and small nucleoli; mitotic activity inconspicuous
Adipocytes have abundant clear cytoplasm with occasional multivacuolation and moderate variability in size; nuclei are monomorphic and peripherally located
Scant collagenous stroma
IHC: MDM2 non-amplified
Hypocellular fascicles of spindle cells with admixed adipocytes
Spindle cells have eosinophilic cytoplasm; nuclei are ovoid with mild-moderate atypia and small nucleoli; mitotic activity inconspicuous
Adipocytes have abundant clear cytoplasm with occasional multivacuolation and moderate variability in size; nuclei are monomorphic and peripherally located
Abundant myxoid-collagenous stroma
IHC: MDM2 non-amplified
Hypocellular fascicles of spindle cells with admixed adipocytes
Spindle cells have eosinophilic cytoplasm; nuclei are ovoid with mild-moderate atypia and small nucleoli; mitotic activity is not conspicuous
Adipocytes have abundant clear cytoplasm with occasional multivacuolation and moderate variability in size; nuclei are monomorphic and peripherally located
Abundant myxoid-collagenous stroma
IHC: negative for MDM2, CDK4
Hypocellular spindle cell neoplasm with a patternless distribution
Spindle-stellate cells have dense eosinophilic cytoplasm; the nuclei are round, hyperchromatic and pleomorphic, with frequent multinucleation; there is occasional mitotic activity
Adipocytes have abundant clear cytoplasm with occasional vacuolation; nuclei are monomorphic and peripherally located
Abundant myxoid-collagenous stroma
FISH: MDM2 non-amplified
Variable cellularity; spindle cells with vague fascicular patttern
Spindle-stellate cells with pale eosinophilic cytoplasm
Round-ovoid nuclei with hyperchromasia, multinucleation and pleomorphism; rare mitotic activity
Adipocytes have abundant clear cytoplasm with occasional vacuolation; nuclei are monomorphic and peripherally located
Myxoid-collagenous stroma; chronic inflammation
FISH: MDM2 non-amplified