CircuLobulated; sheets and anastamosing cords of polygonal -spindle cells
Pale amphophilic cytoplasm
Monomorphic round nuclei with small nucleoli; inconspicuous mitotic activity
Prominent fibromyxoid stroma
IHC: CD34, smooth muscle actin, H-caldesmon
Sheets and anastamosing cords of round-polygonal cells
Pale amphophilic cytoplasm
Monomorphic round nuclei with small nucleoli; inconspicuous mitotic activity
Prominent fibromyxoid stroma
IHC: smooth muscle actin, H-caldesmon, CD34
Circumscribed; sheets of round-polygonal cells
Bright eosinophilic cytoplasm
Monomorphic round nuclei with small nucleoli; inconspicuous mitotic activity
Medium-sized vessels with hyalinized walls
IHC: H-caldesmon
Circumscribed; sheets and anastamosing cords of round-polygonal cells
Pale amphophilic cytoplasm
Monomorphic round nuclei with small nucleoli; inconspicuous mitotic activity
Prominent fibromyxoid stroma
IHC: H-caldesmon
Circumscribed; cords of round-polygonal cells
Bright eosinophilic cytoplasm
Monomorphic round nuclei with small nucleoli; inconspicuous mitotic activity
Prominent medium-large vessels of variable thickness
IHC: H-caldesmon
Circumscribed; sheets-cords of round-polygonal cells
Bright eosinophilic cytoplasm
Monomorphic round nuclei with small nucleoli; inconspicuous mitotic activity
Prominent medium-large vessels of variable thickness
IHC: H-caldesmon
Circumscribed; sheets-cords of round-polygonal cells
Pale eosinophilic cytoplasm
Monomorphic round nuclei with small nucleoli; inconspicuous mitotic activity
Prominent ectatic vessels of variable size and thickness
IHC: H-caldesmon
Lobulated; sheets of round-polygonal cells
Pale amphophilic cytoplasm
Round nuclei with small nucleoli and mild pleomorphism; inconspicuous mitotic activity
IHC: CD34, smooth muscle actin, H-caldesmon
Infiltrative; sheets of round-polygonal cells
Pale amphophilic cytoplasm
Round nuclei with small nucleoli and mild pleomorphism; conspicuous mitotic activity
Necrosis
IHC: H-caldesmon
RNA-seq: MIR143::NOTCH1 gene fusion