Pathology: palmar / plantar fibromatosis
Palmar fibromatosis
Lobulated and infiltrative; fascicles of spindle-stellate cells
Eosinophilic cytoplasmic with long tapering processes
Ovoid wavy nuclei with pinpoint nucleoli; inconspicuous mitotic activity
Abundant collagenous matrix
IHC: beta-catenin
Palmar fibromatosis
Lobulated and infiltrative; spindle-stellate cells with vague fascicular pattern
Eosinophilic cytoplasm with long tapering processes
Ovoid and wavy nuclei with pinpoint nucleoli; inconspicuous mitotic activity
Abundant collagenous matrix with small vessels
Palmar fibromatosis
Lobulated and infiltrative; spindle-stellate cells with vague fascicular pattern
Eosinophilic cytoplasm with long tapering processes
Ovoid and wavy nuclei with pinpoint nucleoli; inconspicuous mitotic activity
Abundant collagenous matrix with small vessels
Plantar fibromatosis
Spindle-stellate cells with vague fascicular pattern
Eosinophilic cytoplasm with long tapering processes
Ovoid and wavy nuclei with pinpoint nucleoli; inconspicuous mitotic activity
Abundant collagenous matrix with small vessels
IHC: smooth muscle actin, beta-catenin
Plantar fibromatosis
Spindle-stellate cells with vague fascicular pattern
Eosinophilic cytoplasm with long tapering processes
Ovoid and wavy nuclei with pinpoint nucleoli; occasional mitotic activity
Abundant collagenous matrix with small vessels
Plantar fibromatosis
Spindle-stellate cells with vague fascicular pattern
Eosinophilic cytoplasm with long tapering processes
Ovoid and elongated nuclei with pinpoint nucleoli; inconspicuous mitotic activity
Collagenous matrix with small vessels
IHC: smooth muscle actin, beta-catenin