Thoracic pathology

Cardiovascular

Hibernoma

  • FISH: MDM2 non-amplified

Intimal sarcoma

  • IHC: MDM2, CDK4

  • FISH: MDM2 amplified

Intimal sarcoma

  • IHC: MDM2, CDK4

  • FISH: MDM2 amplified

Lung

Primary pulmonary myxoid sarcoma

  • IHC: ALK1

  • RNA-seq: EWSR1-CREB1 gene fusion

  • IHC: ALK

  • PMID: 21997693

Primary pulmonary myxoid sarcoma

  • RT-PCR: EWSR1-CREB1 gene fusion

  • PMID: 21997693

Solitary fibrous tumour, primary

  • IHC: CD34, STAT6

  • RNA-seq: NAB2-STAT6 gene fusion

Solitary fibrous tumour, metastatic

  • IHC: STAT6

  • RNA-seq: NAB2-STAT6 gene fusion

Synovial sarcoma

  • IHC: keratin (AE1/AE3)

  • RNA-seq: SS18-SSX2 gene fusion

Undifferentiated pleomorphic sarcoma, metastatic

  • IHC: smooth muscle actin

Mediastinum

Solitary fibrous tumour

  • IHC: CD34, STAT6

  • RNA-seq: NAB2-STAT6 gene fusion

Pleura / pericardium

Liposarcoma, dedifferentiated

  • IHC: MDM2, CDK4

  • FISH: MDM2 amplified

Mesothelioma

  • RNA-seq: EWSR1-ATF1 gene fusion

Mesothelioma

  • RNA-seq: EWSR1-ATF1 gene fusion