Pathology: angiofibroma of soft tissue

Angiofibroma of soft tissue

  • Circumscribed; variable cellularity; spindle cells with patternless arrangement

  • Scant pale eosinophilic cytoplasm

  • Monomorphic ovoid nuclei with small nucleoli; inconspicuous mitotic activity

  • Myxoid-collagenous stroma; complex ramifying capillary-sized vasculature

  • RNA-seq: AHRR-NCOA2 gene fusion

  • PMID: 22301504, 22337624

Angiofibroma of soft tissue

  • Circumscribed; variable cellularity; spindle cells with patternless arrangement

  • Scant pale eosinophilic cytoplasm

  • Monomorphic ovoid nuclei with small nucleoli; inconspicuous mitotic activity

  • Myxoid-collagenous stroma; complex ramifying capillary-sized vasculature

  • RNA-seq: AHRR-NCOA2 gene fusion

  • PMID: 22301504, 22337624