Nests of polygonal cells, surrounded by delicate fibrovascular septa
Abundant granular eosinophilic cytoplasm
Monomorphic round-ovoid nuclei with prominent nucleoli; inconspicuous mitotic activity
IHC: TFE3
FISH: TFE3-rearrangement
Nests of polygonal cells, surrounded by delicate fibrovascular septa
Abundant granular eosinophilic cytoplasm
Monomorphic round-ovoid nuclei with prominent nucleoli; inconspicuous mitotic activity
IHC: TFE3
FISH: ASPSCR1 and TFE3 rearrangement
Epithelioid cells with nested-pseudoalveolar pattern surrounded by delicate fibrovascular septa
Abundant granular eosinophilic cytoplasm
Monomorphic round nuclei with prominent nucleoli; inconspicuous mitotic activity
IHC: TFE3
RNA-seq: ASPSCR1::TFE3 gene fusion
Epithelioid cells with nested-pseudoalveolar pattern surrounded by delicate fibrovascular septa
Abundant amphophilic cytoplasm
Round-ovoid nuclei with moderate pleomorphism, occasional binucleation and prominent nucleoli; inconspicuous mitotic activity
IHC: TFE3
FISH: TFE3-rearrangement