Dermatopathology

Acral angioosteoma cutis

• PMID:  20571346

Angiomyxoma, superficial

• IHC: CD34

• PMID: 34532875

Angiomyxoma, superficial

• IHC: CD34

• PMID: 34532875

Angiosarcoma

• IHC: CD34, ERG,  ALK1

Sun-exposed scalp

Angiosarcoma

• IHC: ERG

Calcinosis cutis (idiopathic)

Cellular neurothekeoma

• IHC: NKI-C3, smooth muscle actin

Cellular neurothekeoma

• IHC: MiTF, NKI-C3

• PMID: 21389838

Cellular neurothekeoma

• IHC: MiTF, NKI-C3

Cellular neurothekeoma

• IHC: smooth muscle actin, NKI-C3

Cutaneous melanocytoma

• IHC: S100, SOX10

• RNA-seq: CRTC1::TRIM11 gene fusion

Dermatofibrosarcoma protuberans, fibrosarcomatous

• IHC: CD34

• RNA-seq: COL1A1::PDGFB gene fusion

Dermatofibrosarcoma protuberans, fibrosarcomatous

• IHC: CD34

• RNA-seq: COL1A1::PDGFB gene fusion

Dermatofibrosarcoma protuberans, fibrosarcomatous

• IHC: CD34. Melan-A

• RNA-seq: COL1A1::PDGFB gene fusion

Dermatomyofibroma

• IHC: smooth muscle actin

Fibrous histiocytoma / Dermatofibroma

Fibrous histiocytoma / Dermatofibroma

• IHC: Factor XIIIa

Fibrous histiocytoma / Dermatofibroma

Fibrous histiocytoma

• IHC: Factor XIIIa, CD34 (NB: peripheral rim enhancement)

Fibrous histiocytoma

• IHC: Factor XIIIa, smooth muscle actin

Fibrous histiocytoma, atypical

• IHC: Factor XIIIa

Fibrous histiocytoma, cellular

Fibrous histiocytoma, cellular

• IHC: Factor XIIIa

Fibrous histiocytoma, cellular

• IHC: Factor XIIIa

Fibrous histiocytoma, epithelioid

• IHC: ALK

• RNA-seq: SQSTM1::ALK  gene fusion

Fibrous histiocytoma, epithelioid

• IHC: ALK, D2-40

Fibrous histiocytoma, epithelioid

• IHC: ALK

• RNA-seq: TPM3-ALK gene fusion

Fibrous histiocytoma, epithelioid

• IHC: ALK

• RNA-seq: EML4::ALK gene fusion

Fibrous histiocytoma, epithelioid

• IHC: ALK

• RNA-seq: SQSTM1::ALK gene fusion

Fibrous histiocytoma, haemosiderotic

Fibrous histiocytoma, haemosiderotic

Fibrous histiocytoma, lipidized

• IHC: Factor XIIIa

Granular cell tumour

• IHC: S100, SOX10, TFE3

Kaposi sarcoma

• IHC: HHV8

Kaposi sarcoma

• IHC: ERG, D2-40, HHV8

Keloid

Leiomyosarcoma / Atypical intradermal smooth muscle neoplasm

• IHC: H-caldesmon

• PMID: 21358302

Leiomyosarcoma / Atypical intradermal smooth muscle neoplasm

• IHC: H-caldesmon

• PMID: 21358302

Leiomyosarcoma

• IHC: H-caldesmon

Leiomyosarcoma

• IHC: H-caldesmon

Low-grade fibromyxoid sarcoma

• RNA-seq: FUS::CREB3L2 gene fusion

Low-grade fibromyxoid sarcoma

• RNA-seq: FUS::CREB3L2 gene fusion

Low-grade fibromyxoid sarcoma

• IHC: MUC4

• RNA-seq: FUS::CREB3L1 gene fusion

Low-grade fibromyxoid sarcoma

• RNA-seq: FUS::CREB3L2 gene fusion

Low-grade myxofibrosarcoma

Myoepithelioma, syncytial

• IHC: S100, smooth muscle actin, epithelial membrane antigen

• RNA-seq: EWSR1::PBX3 gene fusion

Myoepithelioma, syncytial

• IHC: S100, ALK, epithelial membrane antigen

• RNA-seq: EWSR1::PBX3 gene fusion

Nodular fasciitis

• IHC: smooth muscle actin

• RNA-seq: FILIP1L::USP6 gene fusion

Nodular fasciitis

• RNA-seq: MYH9::USP6 gene fusion

Neurofibroma, diffuse

• IHC: CD34, S100, SOX10 

Osteosarcoma, extraskeletal

Plexiform fibrohistiocytic tumour

• IHC: NKI-C3

Pseudomyogenic haemangioendothelioma

• RNA-seq: SERPINE1::FOSB gene fusion

Undifferentiated spindle cell neoplasm

• IHC: smooth muscle actin, CD34, ALK1

• RNA-seq: KLC1::ALK gene fusion

• PMID: 36125853 

Undifferentiated spindle cell neoplasm

• IHC: CD34, ALK1

• RNA-seq: KLC1::ALK gene fusion

• PMID: 36125853