Ectatic thin-walled vessels; polygonal cells with hobnailing
Pale eosinophilic cytoplasm
Hyperchromatic nuclei with moderate pleomorphism; inconspicuous mitotic activity
Multilobulated and infiltrative; spindle-epithelioid cells in vague fascicles
Eosinophilic-amphophilic cytoplasm
Round-ovoid nuclei with prominent nucleoli and moderate pleomorphism; conspicuous mitotic activity
Necrosis; mild lymphocytic infiltrate
IHC: ERG
Anastomosing vessels lined by polygonal-epithelioid cells
Pale eosinophilic cytoplasm
Ovoid nuclei with coarse chromatin, small nucleoli, and moderate pleomorphism; mitotic activity
Occasional solid foci wiht complex multilayering
Multilobulated and infiltrative; spindle-epithelioid cells in nests-fascicles
Amphophilic cytoplasm with occasional vacuoles and erythrocytes
Round-ovoid nuclei with prominent nucleoli and moderate pleomorphism; conspicuous mitotic activity
Mild lymphocytic infiltrate
IHC: c-MYC
Infiltrative; spindle-epithelioid cells in loose fascicles with fenestration
Amphophilic cytoplasm
Ovoid hyperchromatic nuclei with moderate-marked pleomorphism; conspicuous mitotic activity
Mild chronic inflammation; papillary endothelial hyperplasia
IHC: ERG, D2-40