Nests and anastomosing cords of round-polygonal cells
Abundant granular eosinophilic cytoplasm
Round-ovoid nuclei with occasional pseudonuclear inclusions; inconspicuous mitotic activity
Desmoplastic stroma
IHC: S100
Lacks features of malignancy (i.e., sarcomatoid morphology, significant mitosis, geographic necrosis, pleomorphism and increased nuclear:cytoplasmic ratio)
PMID: 9669341
Nests and anastomosing cords of round-polygonal cells
Abundant granular eosinophilic cytoplasm
Round-ovoid nuclei with occasional pseudonuclear inclusions; inconspicuous mitotic activity
Desmoplastic stroma
Lacks features of malignancy (i.e., sarcomatoid morphology, significant mitosis, geographic necrosis, pleomorphism and increased nuclear:cytoplasmic ratio)
PMID: 9669341
Nests and anastomosing cords of polygonal cells
Abundant granular eosinophilic cytoplasm
Round-ovoid nuclei with prominent nucleoli and occasional pseudonuclear inclusions; inconspicuous mitotic activity
Desmoplastic stroma
Lacks features of malignancy (i.e., sarcomatoid morphology, significant mitosis, geographic necrosis, pleomorphism and increased nuclear:cytoplasmic ratio)
PMID: 9669341
Prior history of "granular cell tumour"
Nests and anastomosing cords of round-polygonal cells
Abundant granular eosinophilic cytoplasm
Ovoid hyperchromatic nuclei with mild pleomorphism and occasional pseudonuclear inclusions; mitotic activity
Background bone (i.e., metastasis)
IHC: S100, SOX10