Lobulated; spindle-epithelioid cells with patternless distribution
Pale amphophilic cytoplasm
Round-ovoid nuclei with vesicular chromatin, mild atypia, occasional binucleation; inconspicuous mitotic activity
Chondromyxoid stroma with 'grungy' calcification and foreign-body giant cells; trabeculae of woven bone with osteoblastic rimming
RNA-seq: FN1::FGFR2 gene fusion
Lobulated; hypocellular; spindle-epithelioid cells with patternless distribution
Pale amphophilic cytoplasm
Round-ovoid nuclei with vesicular chromatin, mild atypia, occasional binucleation
Chondromyxoid stroma with 'grungy' calcification and foreign-body giant cells
RNA-seq: FN1::FGFR2 gene fusion
Lobulated; hypocellular
Spindle-epithelioid cells with pale amphophilic cytoplasm
Round-ovoid nuclei with vesicular chromatin, mild atypia, occasional binucleation
Chondromyxoid stroma with 'grungy' calcification and foreign-body giant cells
IHC: D2-40, ERG, S100
RNA-seq: FN1::FGFR2 gene fusion
PMID: 33727696
Lobulated; hypocellular; spindle-epithelioid cells with patternless distribution
Pale amphophilic cytoplasm with indistinct cell borders
Monomorphic ovoid nuclei; inconspicuous mitotic activity
Cartilaginous matrix with so-called "grungy" calcification; interspersed osteoclast-type giant cells
IHC: ERG, D2-40
RNA-seq: FN1::FGFR2 gene fusion
PMID: 33727696
Lobulated; hypocellular; spindle-epithelioid cells with patternless distribution
Pale amphophilic cytoplasm with indistinct cell borders
Monomorphic ovoid nuclei; inconspicuous mitotic activity
Cartilaginous matrix with so-called "grungy" calcification; interspersed osteoclast-type giant cells
RNA-seq: FN1::FGFR1 gene fusion
PMID: 33727696
Lobulated; hypocellular; spindle-epithelioid cells with patternless distribution
Pale amphophilic cytoplasm with indistinct cell borders
Monomorphic ovoid nuclei with occasional binucleation; inconspicuous mitotic activity
Cartilaginous matrix with so-called "grungy" calcification; interspersed osteoclast-type giant cells
IHC: D2-40