Capillary-sized vascular channels with anastomosing sinusoidal pattern
Eosinophilic cytoplasm with occasional hyaline globules
Round-ovoid nuclei with occasional "hobnailing" and mild atypia; inconspicuous mitotic activity
Occasional fibrin thrombi
DNA-seq: GNAQ exon 5 mutation; c.627A>T (p.Gln209His)
Vessels with prominent adipocytic background
Vessels of varying caliber and mural thickness
Endothelial cells are attenuated with eosinophilic cytoplasm, and bland nuclei
Fibrosis; chronic inflammation; atrophic / regenerative skeletal muscle
Lobulated
Large central feeding vessels extend peripherally to small lobules of capillary-sized vessels
Pale amphophilic cytoplasm
Ovoid hyperchromatic nuclei with mild atypia; occasional mitotic activity
Overlying epithelial ulceration
Lobulated
Central feeding vessels extend peripherally to small lobules of capillary-sized vessels
Pale amphophilic cytoplasm
Ovoid nuclei with mild atypia; rare mitotic activity
Centred within vessel lumen
IHC: ERG, CD31
PMID: 575269
Lobulated
Central feeding vessels extend peripherally to small lobules of capillary-sized vessels
Pale amphophilic cytoplasm
Ovoid nuclei with mild atypia; rare mitotic activity
Centred within vessel lumen
PMID: 575269
Lobulated; congested ectatic and anastomosing vascular spaces lined by endothelial monolayer
Eosinophilic cytoplasm
Monomorphic ovoid hyperchromatic nuclei; inconspicuous mitotic activity
Centrally prominent papillary endothelial hyperplasia
PMID: 1746680
Lobulated; fascicles of spindle cells admixed with vasoformative areas ranging from small and solid clusters to patulous thin walled channels
Eosinophilic cytoplasm, occasional vacuolation and rare hyaline inclusions
Ovoid nuclei with minimal pleomorphism; inconspicuous mitotic activity
Circumscribed
Admixture of capillary-like and cavernous vascular channels
Endothelial cells are attenuated with eosinophilic cytoplasm
Monomorphic ovoid nuclei; inconspicuous mitotic activity
Congested and dilated vessels; focal myxoid stroma