Pathology: superficial CD34-positive fibroblastic tumour

Superficial CD34-positive fibroblastic tumour

  • Relatively circumscribed; fascicles of spindle-epithelioid cells

  • Abundant "glassy" eosinophilic cytoplasm

  • Ovoid nuclei with moderate pleomorphism, occasional pseudonuclear inclusions and macronucleoli; inconspicuous mitotic activity

  • Focal bands of collagenous stroma; mild chronic inflammatory infiltrate

  • IHC: CD34, keratin (AE1/AE3)

  • RNA-seq: negative