Multinodular; spindle cell fascicles
Amphophilic cytoplasm with occasional hyaline globules
Monomorphic ovoid nuclei with small nucleoli; mitotic activity
IHC: ERG, HHV8
Spindle cell fascicles
Amphophilic cytoplasm with occasional hyaline globules
Monomorphic ovoid nuclei with small nucleoli; mitotic activity
IHC: HHV8
Spindle cell fascicles
Amphophilic cytoplasm with occasional hyaline globules
Monomorphic ovoid nuclei with small nucleoli; mitotic activity
IHC: ERG, HHV8
Spindle cell fascicles-whorls
Amphophilic cytoplasm with occasional hyaline globules
Monomorphic ovoid nuclei with small nucleoli; mitotic activity
Necrosis; mild chronic inflammatory infiltrate
IHC: CD31, HHV8 (x2)*
* NB: speckled pattern on higher magnification
Spindle cell fascicles
Amphophilic cytoplasm with occasional hyaline globules
Monomorphic ovoid nuclei with small nucleoli; mitotic activity
Brisk lymphoplasmacytic inflammatory infiltrate; interstitial haemorrhage with abundant siderophages
IHC: HHV8
Spindle cell fascicles
Amphophilic cytoplasm with occasional hyaline globules
Monomorphic ovoid nuclei with small nucleoli; mitotic activity
Mild lymphoplasmacytic inflammatory infiltrate; interstitial haemorrhage with occasional siderophages
IHC: HHV8
Spindle cell fascicles-whorls
Eosinophilic-amphophilic cytoplasm with occasional clear vacuoles and hyaline globules
Monomorphic ovoid nuclei with small nucleoli; mitotic activity
Minimal chronic inflammation
IHC: ERG, HHV8
Nests of epithelioid cells focally lining slit-like spaces
Amphophilic cytoplasm with occasional hyaline globules
Hyperchromatic round-ovoid nuclei with mild atypia and prominent small nucleoli; mitotic activity
"Crush" artifact; apoptotic debris; mild chronic inflammatory infiltrate
IHC: ERG, HHV8